Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B.
Two palladium-catalysed amination protocols are deployed in the desymmetrisation of the complex dimeric alkaloid meso-chimonanthine. The power of these transformations is showcased in an efficient formal and total synthesis of the natural products hodgkinsine and hodgkinsine B, respectively.
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2012
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| _version_ | 1826281463439425536 |
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| author | Snell, R Durbin, M Woodward, R Willis, M Snell, R Durbin, M Woodward, R Willis, M |
| author_facet | Snell, R Durbin, M Woodward, R Willis, M Snell, R Durbin, M Woodward, R Willis, M |
| author_sort | Snell, R |
| collection | OXFORD |
| description | Two palladium-catalysed amination protocols are deployed in the desymmetrisation of the complex dimeric alkaloid meso-chimonanthine. The power of these transformations is showcased in an efficient formal and total synthesis of the natural products hodgkinsine and hodgkinsine B, respectively. |
| first_indexed | 2024-03-07T00:29:11Z |
| format | Journal article |
| id | oxford-uuid:7f2df1f6-3328-4f50-b018-d964ca7b3713 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:29:11Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:7f2df1f6-3328-4f50-b018-d964ca7b37132022-03-26T21:15:06ZCatalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7f2df1f6-3328-4f50-b018-d964ca7b3713total synthesisChemistry and allied sciencesdesymmetrizationnatural productsheterocyclesalkaloidsEnglishSymplectic Elements at Oxford2012Snell, RDurbin, MWoodward, RWillis, MSnell, RDurbin, MWoodward, RWillis, MTwo palladium-catalysed amination protocols are deployed in the desymmetrisation of the complex dimeric alkaloid meso-chimonanthine. The power of these transformations is showcased in an efficient formal and total synthesis of the natural products hodgkinsine and hodgkinsine B, respectively. |
| spellingShingle | total synthesis Chemistry and allied sciences desymmetrization natural products heterocycles alkaloids Snell, R Durbin, M Woodward, R Willis, M Snell, R Durbin, M Woodward, R Willis, M Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B. |
| title | Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B. |
| title_full | Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B. |
| title_fullStr | Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B. |
| title_full_unstemmed | Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B. |
| title_short | Catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine B. |
| title_sort | catalytic enantioselective desymmetrisation as a tool for the synthesis of hodgkinsine and hodgkinsine b |
| topic | total synthesis Chemistry and allied sciences desymmetrization natural products heterocycles alkaloids |
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