Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

Eitemau Tebyg

• Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer.
  gan: Cerletti, M, et al.
  Cyhoeddwyd: (2003)
• Up-regulation of utrophin alleviates the dystrophic phenotype in the mdx mouse heart
  gan: Sang, E, et al.
  Cyhoeddwyd: (2000)
• The utrophin and dystrophin genes share similarities in genomic structure.
  gan: Pearce, M, et al.
  Cyhoeddwyd: (1993)
• Confirmation by immunogold labeling that utrophin is localised to the normal position of dystrophin in dystrophin-negative transgenic mouse muscle
  gan: Cullen, M, et al.
  Cyhoeddwyd: (2001)
• Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity
  gan: Justin P. Hardee, et al.
  Cyhoeddwyd: (2021-03-01)