Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disorder caused by the lack of a subsarcolemmal protein, dystrophin. We have previously shown that the dystrophin-related protein, utrophin is able to compensate for the lack of dystrophin in the mdx mouse, the mouse model for DMD. He...

詳細記述

書誌詳細
主要な著者: Wakefield, P, Tinsley, J, Wood, M, Gilbert, R, Karpati, G, Davies, K
フォーマット: Journal article
言語:English
出版事項: 2000