Abnormal puberty in paediatric Cushing's disease: relationship with adrenal androgen, sex hormone binding globulin and gonadotrophin concentrations.

Abnormal puberty in paediatric Cushing's disease: relationship with adrenal androgen, sex hormone binding globulin and gonadotrophin concentrations.

OBJECTIVE: Paediatric Cushing's disease is frequently associated with abnormal puberty. We addressed the hypothesis that prepubertal patients show excessive virilization and pubertal patients show suppression of LH and FSH secretion. DESIGN AND MEASUREMENTS: Serum androstenedione (A4), dehydroe...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Dupuis, C, Storr, H, Perry, L, Ho, J, Ahmed, L, Ong, K, Dunger, D, Monson, J, Grossman, AB, Besser, G, Savage, M
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2007

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Changes in gonadotrophin secretion during childhood and puberty.
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Prepubertal Cushing's disease: diagnosis, management and therapeutic outcome
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The effect of naloxone on pulsatile gonadotrophin release in normal subjects.
gan: Moult, P, et al.
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Growth in disorders of adrenal hyperfunction.
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Benzodiazepines attenuate the pituitary-adrenal responses to corticotrophin-releasing hormone in healthy volunteers, but not in patients with Cushing's syndrome.
gan: Korbonits, M, et al.
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Diagnosis and treatment of Cushing's disease in children.
gan: Savage, M, et al.
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CRF in the differential diagnosis of Cushing's syndrome: a comparison with the dexamethasone suppression test.
gan: Grossman, AB, et al.
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