SDH mutations in cancer

The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...

Descrizione completa

Dettagli Bibliografici
Autori principali: Bardella, C, Pollard, P, Tomlinson, I
Natura: Journal article
Lingua:English
Pubblicazione: 2011

Documenti analoghi