SDH mutations in cancer

SDH mutations in cancer

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The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...

Полное описание

Библиографические подробности
Главные авторы:	Bardella, C, Pollard, P, Tomlinson, I
Формат:	Journal article
Язык:	English
Опубликовано:	2011

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