SDH mutations in cancer

The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...

詳細記述

書誌詳細
主要な著者: Bardella, C, Pollard, P, Tomlinson, I
フォーマット: Journal article
言語:English
出版事項: 2011