Nucleoporin 54 contributes to Homologous recombination repair and post-replicative DNA integrity

Nucleoporin 54 contributes to Homologous recombination repair and post-replicative DNA integrity

The nuclear pore complex (NPC) machinery is emerging as an important determinant in the maintenance of genome integrity and sensitivity to DNA double-strand break (DSB)-inducing agents, such as ionising radiation (IR). In this study, using a high-throughput siRNA screen, we identified the central ch...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Rodriguez-Berriguete, G, Granata, G, Puliyadi, R, Tiwana, G, Prevo, R, Wilson, R, Yu, S, Buffa, F, Humphrey, T, McKenna, W, Higgins, G
Μορφή:	Journal article
Έκδοση:	Oxford University Press 2018

Παρόμοια τεκμήρια

Targeting TOPK 1 sensitises tumour cells to radiation-induced damage by enhancing replication stress
ανά: Herbert, K, κ.ά.
Έκδοση: (2020)

The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress
ανά: Coates, JTT, κ.ά.
Έκδοση: (2020)

Depletion of Signal Recognition Particle 72kDa increases radiosensitivity
ανά: Prevo, R, κ.ά.
Έκδοση: (2017)

CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner
ανά: Prevo, R, κ.ά.
Έκδοση: (2018)

Homologous recombination repair rathway and RAD54L in early-stage lung adenocarcinoma
ανά: Shaopeng Zheng, κ.ά.
Έκδοση: (2021-02-01)

Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
ανά: Donna R. Whelan, κ.ά.
Έκδοση: (2018-09-01)

Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
ανά: Nicolay, N, κ.ά.
Έκδοση: (2012)

The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast.
ανά: Doe, C, κ.ά.
Έκδοση: (2004)

Competition between replicative and translesion polymerases during homologous recombination repair in Drosophila.
ανά: Daniel P Kane, κ.ά.
Έκδοση: (2012-01-01)

A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
ανά: Ahrabi, S, κ.ά.
Έκδοση: (2016)

The role of <it>Candida albicans </it>homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity
ανά: White Theodore C, κ.ά.
Έκδοση: (2011-09-01)

Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
ανά: Higgins, G, κ.ά.
Έκδοση: (2010)

DNA ADP-ribosylation stalls replication and is reversed by RecF-mediated homologous recombination and nucleotide excision repair
ανά: Lawarée, E, κ.ά.
Έκδοση: (2020)

Antitumour effect of the mitochondrial complex III inhibitor Atovaquone in combination with anti-PD-L1 therapy in mouse cancer models
ανά: Gonzalo Rodriguez-Berriguete, κ.ά.
Έκδοση: (2024-01-01)

Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress.
ανά: Gangarao Davuluri, κ.ά.
Έκδοση: (2008-10-01)

The human nucleoporin Tpr protects cells from RNA-mediated replication stress
ανά: Martin Kosar, κ.ά.
Έκδοση: (2021-06-01)

Screening for inhibitors of and novel proteins within the homologous recombination DNA repair pathway
ανά: Kingham, G
Έκδοση: (2012)

DNA-RNA hybrids at DSBs interfere with repair by homologous recombination
ανά: Pedro Ortega, κ.ά.
Έκδοση: (2021-07-01)

Expression of EhRAD54, EhRAD51, and EhBLM proteins during DNA repair by homologous recombination in Entamoeba histolytica
ανά: del Socorro Charcas-Lopez Ma., κ.ά.
Έκδοση: (2014-01-01)

The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
ανά: Qin Zhou, κ.ά.
Έκδοση: (2020-05-01)

Nucleoporin mediated nuclear positioning and silencing of HMR.
ανά: Giulia J Ruben, κ.ά.
Έκδοση: (2011-01-01)

The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination
ανά: Jac A. Nickoloff, κ.ά.
Έκδοση: (2021-09-01)

DNA Topoisomerase 3α Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi
ανά: Héllida Marina Costa-Silva, κ.ά.
Έκδοση: (2021-05-01)

Regulators of Homologous Recombination Repair as Novel Targets for Cancer Treatment
ανά: Małgorzata ekrajewska, κ.ά.
Έκδοση: (2015-03-01)

Leveraging homologous recombination repair deficiency in sarcoma
ανά: Dea Slade, κ.ά.
Έκδοση: (2023-03-01)

Investigation into the relationship between PARPs in DNA repair and synthetic lethality with homologous recombination deficiency
ανά: Ronson, G
Έκδοση: (2017)

DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair
ανά: Emeline Lawarée, κ.ά.
Έκδοση: (2020-02-01)

Recovery of arrested replication forks by homologous recombination is error-prone.
ανά: Ismail Iraqui, κ.ά.
Έκδοση: (2012-01-01)

Two Nucleoporin98 homologous genes jointly participate in the regulation of starch degradation to repress senescence in Arabidopsis
ανά: Long Xiao, κ.ά.
Έκδοση: (2020-06-01)

Author Correction: The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
ανά: Qin Zhou, κ.ά.
Έκδοση: (2022-11-01)

The paradoxical role of nucleoporins in tumourigenesis
Έκδοση: (2022-03-01)

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
ανά: Yuehan Wu, κ.ά.
Έκδοση: (2015-12-01)

Homologous recombinant repair gene mutations across tumors
ανά: Marc Weiner, κ.ά.
Έκδοση: (2024-01-01)

Involvement of Escherichia coli DNA Replication Proteins in Phage Lambda Red-Mediated Homologous Recombination.
ανά: Anthony R Poteete
Έκδοση: (2013-01-01)

Prion formation by a yeast GLFG nucleoporin
ανά: Halfmann, Randal Arthur, κ.ά.
Έκδοση: (2014)

Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery
ανά: Audrey Costes, κ.ά.
Έκδοση: (2012-12-01)

Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer
ανά: Andrew J. Wilson, κ.ά.
Έκδοση: (2022-02-01)

External beam radiation therapy and enadenotucirev: Inhibition of the DDR and mechanisms of radiation-mediated virus increase
ανά: Pokrovska, TD, κ.ά.
Έκδοση: (2020)

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination
ανά: Chiara Di Dio, κ.ά.
Έκδοση: (2023-05-01)

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution
ανά: Ulrich, Alexander, κ.ά.
Έκδοση: (2014)