Nucleoporin 54 contributes to Homologous recombination repair and post-replicative DNA integrity

Nucleoporin 54 contributes to Homologous recombination repair and post-replicative DNA integrity

The nuclear pore complex (NPC) machinery is emerging as an important determinant in the maintenance of genome integrity and sensitivity to DNA double-strand break (DSB)-inducing agents, such as ionising radiation (IR). In this study, using a high-throughput siRNA screen, we identified the central ch...

Bibliografske podrobnosti
Main Authors:	Rodriguez-Berriguete, G, Granata, G, Puliyadi, R, Tiwana, G, Prevo, R, Wilson, R, Yu, S, Buffa, F, Humphrey, T, McKenna, W, Higgins, G
Format:	Journal article
Izdano:	Oxford University Press 2018

Podobne knjige/članki

Targeting TOPK 1 sensitises tumour cells to radiation-induced damage by enhancing replication stress
od: Herbert, K, et al.
Izdano: (2020)

The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress
od: Coates, JTT, et al.
Izdano: (2020)

Depletion of Signal Recognition Particle 72kDa increases radiosensitivity
od: Prevo, R, et al.
Izdano: (2017)

CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner
od: Prevo, R, et al.
Izdano: (2018)

Homologous recombination repair rathway and RAD54L in early-stage lung adenocarcinoma
od: Shaopeng Zheng, et al.
Izdano: (2021-02-01)

Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
od: Donna R. Whelan, et al.
Izdano: (2018-09-01)

Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
od: Nicolay, N, et al.
Izdano: (2012)

The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast.
od: Doe, C, et al.
Izdano: (2004)

Competition between replicative and translesion polymerases during homologous recombination repair in Drosophila.
od: Daniel P Kane, et al.
Izdano: (2012-01-01)

A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
od: Ahrabi, S, et al.
Izdano: (2016)

The role of <it>Candida albicans </it>homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity
od: White Theodore C, et al.
Izdano: (2011-09-01)

Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
od: Higgins, G, et al.
Izdano: (2010)

DNA ADP-ribosylation stalls replication and is reversed by RecF-mediated homologous recombination and nucleotide excision repair
od: Lawarée, E, et al.
Izdano: (2020)

Antitumour effect of the mitochondrial complex III inhibitor Atovaquone in combination with anti-PD-L1 therapy in mouse cancer models
od: Gonzalo Rodriguez-Berriguete, et al.
Izdano: (2024-01-01)

Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress.
od: Gangarao Davuluri, et al.
Izdano: (2008-10-01)

The human nucleoporin Tpr protects cells from RNA-mediated replication stress
od: Martin Kosar, et al.
Izdano: (2021-06-01)

Screening for inhibitors of and novel proteins within the homologous recombination DNA repair pathway
od: Kingham, G
Izdano: (2012)

DNA-RNA hybrids at DSBs interfere with repair by homologous recombination
od: Pedro Ortega, et al.
Izdano: (2021-07-01)

Expression of EhRAD54, EhRAD51, and EhBLM proteins during DNA repair by homologous recombination in Entamoeba histolytica
od: del Socorro Charcas-Lopez Ma., et al.
Izdano: (2014-01-01)

The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
od: Qin Zhou, et al.
Izdano: (2020-05-01)

Nucleoporin mediated nuclear positioning and silencing of HMR.
od: Giulia J Ruben, et al.
Izdano: (2011-01-01)

The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination
od: Jac A. Nickoloff, et al.
Izdano: (2021-09-01)

DNA Topoisomerase 3α Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi
od: Héllida Marina Costa-Silva, et al.
Izdano: (2021-05-01)

Regulators of Homologous Recombination Repair as Novel Targets for Cancer Treatment
od: Małgorzata ekrajewska, et al.
Izdano: (2015-03-01)

Leveraging homologous recombination repair deficiency in sarcoma
od: Dea Slade, et al.
Izdano: (2023-03-01)

Investigation into the relationship between PARPs in DNA repair and synthetic lethality with homologous recombination deficiency
od: Ronson, G
Izdano: (2017)

DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair
od: Emeline Lawarée, et al.
Izdano: (2020-02-01)

Recovery of arrested replication forks by homologous recombination is error-prone.
od: Ismail Iraqui, et al.
Izdano: (2012-01-01)

Two Nucleoporin98 homologous genes jointly participate in the regulation of starch degradation to repress senescence in Arabidopsis
od: Long Xiao, et al.
Izdano: (2020-06-01)

Author Correction: The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
od: Qin Zhou, et al.
Izdano: (2022-11-01)

The paradoxical role of nucleoporins in tumourigenesis
Izdano: (2022-03-01)

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.
od: Yuehan Wu, et al.
Izdano: (2015-12-01)

Homologous recombinant repair gene mutations across tumors
od: Marc Weiner, et al.
Izdano: (2024-01-01)

Involvement of Escherichia coli DNA Replication Proteins in Phage Lambda Red-Mediated Homologous Recombination.
od: Anthony R Poteete
Izdano: (2013-01-01)

Prion formation by a yeast GLFG nucleoporin
od: Halfmann, Randal Arthur, et al.
Izdano: (2014)

Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery
od: Audrey Costes, et al.
Izdano: (2012-12-01)

Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer
od: Andrew J. Wilson, et al.
Izdano: (2022-02-01)

External beam radiation therapy and enadenotucirev: Inhibition of the DDR and mechanisms of radiation-mediated virus increase
od: Pokrovska, TD, et al.
Izdano: (2020)

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination
od: Chiara Di Dio, et al.
Izdano: (2023-05-01)

The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution
od: Ulrich, Alexander, et al.
Izdano: (2014)