Measurement of the noncomplexed free fraction of tissue inhibitor of metalloproteinases 1 in plasma by immunoassay.

BACKGROUND: We previously found differences in total concentrations of tissue inhibitor of metalloproteinases 1 (TIMP-1) in plasma from donors and cancer patients. Because TIMP-1 can exist in more than one molecular form, a new immunoassay to specifically detect free TIMP-1 was developed and concen...

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Bibliographic Details
Main Authors: Holten-Andersen, M, Christensen, I, Nielsen, H, Lilja, H, Murphy, G, Jensen, V, Brünner, N, Piironen, T
Format: Journal article
Language:English
Published: 2002