T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies.
Two different bispecific hybrid antibodies were generated by cell fusion of pairs of existing hybrid-myeloma cell lines. Both hybrid antibodies had similar specificity for human CD3 and mouse Thy-1 but differed in the isotypes of the immunoglobulin heavy chains. Hybrid HA2b/2b was a hybrid between a...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
1987
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