T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies.

Two different bispecific hybrid antibodies were generated by cell fusion of pairs of existing hybrid-myeloma cell lines. Both hybrid antibodies had similar specificity for human CD3 and mouse Thy-1 but differed in the isotypes of the immunoglobulin heavy chains. Hybrid HA2b/2b was a hybrid between a...

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Bibliographic Details
Main Authors: Clark, MR, Waldmann, H
Format: Journal article
Language:English
Published: 1987