T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies.

Two different bispecific hybrid antibodies were generated by cell fusion of pairs of existing hybrid-myeloma cell lines. Both hybrid antibodies had similar specificity for human CD3 and mouse Thy-1 but differed in the isotypes of the immunoglobulin heavy chains. Hybrid HA2b/2b was a hybrid between a...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Clark, MR, Waldmann, H
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1987