Robust phosphoproteome enrichment using monodisperse microsphere-based immobilized titanium (IV) ion affinity chromatography.

Mass spectrometry (MS)-based proteomics has become the preferred tool for the analysis of protein phosphorylation. To be successful at such an endeavor, there is a requirement for an efficient enrichment of phosphopeptides. This is necessary because of the substoichiometric nature of phosphorylation...

Full description

Bibliographic Details
Main Authors: Zhou, H, Ye, M, Dong, J, Corradini, E, Cristobal, A, Heck, A, Zou, H, Mohammed, S
Format: Journal article
Language:English
Published: 2013