Defect in Ser312 phosphorylation of Tp53 dysregulates lipid metabolism for fatty accumulation and fatty liver susceptibility: Revealed by lipidomics

The <i>Tp53</i> gene is a well-known tumour suppressor, mutation of which (e.g. prevention of Ser312 phosphorylation) induces deletion or expression of an inactive <i>p53</i> protein to increase the susceptibility of tumour occurance. However, the role of <i>Tp53</i&...

Full description

Bibliographic Details
Main Authors: He, M, Slee, EA, Sun, M, Hu, C, Chang, W-T, Xu, G, Lu, X, Wang, M
Format: Journal article
Language:English
Published: Elsevier 2022