Deletion of fifteen open reading frames from modified vaccinia virus Ankara fails to improve immunogenicity

Modified vaccinia virus Ankara (MVA) is a highly attenuated strain of vaccinia virus, which has been used as a recombinant vaccine vector in many vaccine development programmes. The loss of many immunosuppressive and host-range genes resulted in a safe and immunogenic vaccine vector. However it stil...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Alharbi, N, Spencer, A, Hill, A, Gilbert, S
التنسيق: Journal article
اللغة:English
منشور في: Public Library of Science 2015