The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response

The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response

The emergence and spread of artemisinin resistant Plasmodium falciparum , first in the Greater Mekong Subregion (GMS), and now in East Africa, is a major threat to global malaria eliminations ambitions. To investigate the artemisinin resistance mechanism, transcriptome analysis was conducted of 577...

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Bibliographic Details
Main Authors: Zhu, L, Pluijm, RVD, Kucharski, M, Nayak, S, Tripathi, J, Nosten, F, Faiz, A, Amaratunga, C, Lek, D, Ashley, E, Smithuis, F, Phyo, AP, Lin, K, Imwong, M, Mayxay, M, Dhorda, M, Chau, NH, Thuy, NNTT, Newton, P, Jittamala, P, Tripura, R, Pukrittayakamee, S, Peto, T, Miotto, O, von Seidlein, L, Hien, TT, Ginsburg, H, Day, NPJ, White, N, Dondorp, A, Bozdech, Z
Format: Working paper
Language:English
Published: bioRxiv 2021

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