Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): establishing a group A Streptococcus pharyngitis human infection study

Group A Streptococcus (GAS) is a highly-adapted and human-restricted pathogen responsible for a high global burden of disease across a diverse clinical spectrum. Vaccine development has been impeded by scientific, regulatory, and commercial obstacles. Human infection studies (HIS) are increasingly c...

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Bibliographic Details
Main Authors: Osowicki, J, Azzopardi, KI, Baker, C, Waddington, CS, Pandey, M, Schuster, T, Grobler, A, Cheng, AC, Pollard, AJ, McCarthy, JS, Good, MF, Walker, MJ, Dale, JB, Batzloff, MR, Carapetis, JR, Smeesters, PR, Steer, AC
Format: Journal article
Language:English
Published: Elsevier 2019