Suppressive effects of the anti-oxidant N-acetylcysteine on the anti-malarial activity of artesunate.

The anti-oxidant drug N-acetylcysteine (NAC) has been proposed as adjunctive treatment in severe falciparum malaria. However, this might inhibit the anti-malarial drug action of the artemisinins, which are thought to exert their parasitocidal action through oxidative damage. We studied the interacti...

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Bibliographic Details
Main Authors: Arreesrisom, P, Dondorp, A, Looareesuwan, S, Udomsangpetch, R
Format: Journal article
Language:English
Published: 2007