Toll-like receptor responses in IRAK-4-deficient neutrophils.

Human neutrophils were found to express all known Toll-like receptors (TLRs) except TLR3 and TLR7. IRAK-4-deficient neutrophils were tested for their responsiveness to various TLR ligands. Essentially all TLR responses in neutrophils, including the induction of reactive oxygen species generation, ad...

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Bibliographic Details
Main Authors: van Bruggen, R, Drewniak, A, Tool, A, Jansen, M, van Houdt, M, Geissler, J, van den Berg, T, Chapel, H, Kuijpers, T
Format: Journal article
Language:English
Published: 2010