Toll-like receptor responses in IRAK-4-deficient neutrophils.
Human neutrophils were found to express all known Toll-like receptors (TLRs) except TLR3 and TLR7. IRAK-4-deficient neutrophils were tested for their responsiveness to various TLR ligands. Essentially all TLR responses in neutrophils, including the induction of reactive oxygen species generation, ad...
Main Authors: | van Bruggen, R, Drewniak, A, Tool, A, Jansen, M, van Houdt, M, Geissler, J, van den Berg, T, Chapel, H, Kuijpers, T |
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Format: | Journal article |
Language: | English |
Published: |
2010
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