Activation of the HIF pathway in cancer.
The maintenance of oxygen homeostasis is required both in physiological development and tumour growth. Hypoxia inducible factor (HIF) plays a central role in both processes. Reliable methods for visualising HIF alpha subunits have established that HIF activation occurs in the majority of common canc...
Main Authors: | , , |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2001
|