Activation of the HIF pathway in cancer.

Activation of the HIF pathway in cancer.

The maintenance of oxygen homeostasis is required both in physiological development and tumour growth. Hypoxia inducible factor (HIF) plays a central role in both processes. Reliable methods for visualising HIF alpha subunits have established that HIF activation occurs in the majority of common canc...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Maxwell, P, Pugh, C, Ratcliffe, P
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2001

Παρόμοια τεκμήρια

The HIF pathway: implications for patterns of gene expression in cancer.
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Hypoxia and HIF pathway in cancer and the placenta
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Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
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Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway.
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Έκδοση: (2017-07-01)

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ATF5 and HIF1α cooperatively activate HIF1 signaling pathway in esophageal cancer
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Έκδοση: (2021-05-01)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
ανά: Cockman, M, κ.ά.
Έκδοση: (2019)

Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma.
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Έκδοση: (2009)

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