Activation of the HIF pathway in cancer.

Activation of the HIF pathway in cancer.

The maintenance of oxygen homeostasis is required both in physiological development and tumour growth. Hypoxia inducible factor (HIF) plays a central role in both processes. Reliable methods for visualising HIF alpha subunits have established that HIF activation occurs in the majority of common canc...

Полное описание

Библиографические подробности
Главные авторы:	Maxwell, P, Pugh, C, Ratcliffe, P
Формат:	Journal article
Язык:	English
Опубликовано:	2001

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