Activation of the HIF pathway in cancer.

Activation of the HIF pathway in cancer.

The maintenance of oxygen homeostasis is required both in physiological development and tumour growth. Hypoxia inducible factor (HIF) plays a central role in both processes. Reliable methods for visualising HIF alpha subunits have established that HIF activation occurs in the majority of common canc...

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Bibliografiska uppgifter
Huvudupphovsmän:	Maxwell, P, Pugh, C, Ratcliffe, P
Materialtyp:	Journal article
Språk:	English
Publicerad:	2001

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