Activation of the HIF pathway in cancer.

The maintenance of oxygen homeostasis is required both in physiological development and tumour growth. Hypoxia inducible factor (HIF) plays a central role in both processes. Reliable methods for visualising HIF alpha subunits have established that HIF activation occurs in the majority of common canc...

Полное описание

Библиографические подробности
Главные авторы: Maxwell, P, Pugh, C, Ratcliffe, P
Формат: Journal article
Язык:English
Опубликовано: 2001