The val158met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease.

We investigated whether the val(158)met functional polymorphism of catechol-o-methyltransferase influenced age-related changes in grey matter density and volume, both in healthy individuals (n=80, ages 18-79) and those with Parkinson's disease (n=50). Global grey matter volumes and voxelwise es...

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Bibliographic Details
Main Authors: Rowe, J, Hughes, L, Williams-Gray, C, Bishop, S, Fallon, S, Barker, R, Owen, A
Format: Journal article
Language:English
Published: 2010