Synthesis of (-)-(Z)-deoxypukalide.

Synthesis of (-)-(Z)-deoxypukalide.

(Chemical Equation Presented) Closing the deal: A ring-closing metathesis (RCM)/aromatization protocol, followed by a regioselective Negishi cross-coupling reaction and macrolactonization, with subsequent RCM mediate the synthesis of (-)-(Z)-deoxypukalide in 12 linear steps and 15% overall yield (se...

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Bibliographic Details
Main Authors:	Donohoe, T, Ironmonger, A, Kershaw, N
Format:	Journal article
Language:	English
Published:	2008

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