Alternative vaccine administration by powder injection: Needle-free dermal delivery of the glycoconjugate meningococcal group Y vaccine

Powder-injectors use gas propulsion to deposit lyophilised drug or vaccine particles in the epidermal and sub epidermal layers of the skin. We prepared dry-powder (Tg = 45.2 ± 0.5°C) microparticles (58.1 μm) of a MenY-CRM197 glyconjugate vaccine (0.5% wt.) for intradermal needle-free powder injectio...

Полное описание

Библиографические подробности
Главные авторы: Weissmueller, N, Marsay, L, Schiffter, H, Carlisle, R, Rollier, C, Prud'homme, R, Pollard, A
Формат: Journal article
Язык:English
Опубликовано: Public Library of Science 2017