Effects of the alpha-mannosidase inhibitors, 1,4-dideoxy-1,4-imino-D-mannitol and swainsonine, on glycoprotein catabolism in cultured macrophages.

Effects of the alpha-mannosidase inhibitors, 1,4-dideoxy-1,4-imino-D-mannitol and swainsonine, on glycoprotein catabolism in cultured macrophages.

Thioglycollate-stimulated murine peritoneal macrophages were cultured for eight days in the presence of swainsonine, or 1,4-dideoxy-1,4-imino-D-mannitol (DIM), or both of these competitive alpha-mannosidase inhibitors together. Analysis of accumulated high-mannose oligosaccharides by reversed phase...

書誌詳細
主要な著者:	Daniel, P, Newburg, D, O'Neil, N, Smith, P, Fleet, G
フォーマット:	Journal article
言語:	English
出版事項:	1989

類似資料

1,4-Dideoxy-1,4-imino-D-mannitol inhibits glycoprotein processing and mannosidase.
著者:: Palamarczyk, G, 等
出版事項: (1985)

INHIBITION OF ALPHA-MANNOSIDASE ACTIVITY BY 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL
著者:: Elbein, A, 等
出版事項: (1985)

DESIGN SYNTHESIS AND PRELIMINARY EVALUATION OF A POTENT ALPHA-MANNOSIDASE INHIBITOR - 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL
著者:: Fleet, G, 等
出版事項: (1984)

SYNTHESIS OF THE ALPHA-MANNOSIDASE INHIBITORS SWAINSONINE [(1S, 2R, 8R, 8AR)-1,2,8-TRIHYDROXYOCTAHYDROINDOLIZINE] AND 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL FROM MANNOSE
著者:: Bashyal, B, 等
出版事項: (1987)

SYNTHESIS FROM D-MANNOSE OF 1,4-DIDEOXY-1,4-IMINO-L-RIBITOL AND OF THE ALPHA-MANNOSIDASE INHIBITOR 1,4-DIDEOXY-1,4-IMINO-D-TALITOL
著者:: Fleet, G, 等
出版事項: (1988)

Looking glass inhibitors: synthesis of a potent naringinase inhibitor L-DIM [1,4-dideoxy-1,4-imino-L-mannitol], the enantiomer of DIM [1,4-dideoxy-1,4-imino-D-mannitol] a potent alpha-D-mannosidase inhibitor
著者:: Hakansson, A, 等
出版事項: (2007)

SYNTHESIS OF THE MANNOSIDASE INHIBITORS SWAINSONINE AND 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL AND OF THE RING CONTRACTED SWAINSONINES, (1S, 2R, 7R, 7AR)-1,2,7-TRIHYDROXYPYRROLIZIDINE AND (1S, 2R, 7S, 7AR)-1,2,7-TRIHYDROXYPYRROLIZIDINE
著者:: Carpenter, N, 等
出版事項: (1989)

THE SYNTHESIS FROM D-XYLOSE OF THE POTENT AND SPECIFIC ENANTIOMERIC GLUCOSIDASE INHIBITORS, 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL AND 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL
著者:: Fleet, G, 等
出版事項: (1986)

Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol.
著者:: Araújo, N, 等
出版事項: (2012)

Inhibition of the alpha-L-arabinofuranosidase III of Monilinia fructigena by 1,4-dideoxy-1,4-imino-L-threitol and 1,4-dideoxy-1,4-imino-L-arabinitol.
著者:: Axamawaty, M, 等
出版事項: (1990)

POTENT COMPETITIVE-INHIBITION OF ALPHA-GALACTOSIDASE AND ALPHA-GLUCOSIDASE ACTIVITY BY 1,4-DIDEOXY-1,4-IMINOPENTITOLS - SYNTHESES OF 1,4-DIDEOXY-1,4-IMINO-D-LYXITOL AND OF BOTH ENANTIOMERS OF 1,4-DIDEOXY-1,4-IMINOARABINITOL
著者:: Fleet, G, 等
出版事項: (1985)

POLYHYDROXYLATED PYRROLIDINES FROM SUGAR LACTONES - SYNTHESIS OF 1,4-DIDEOXY-1,4-IMINO-D-GLUCITOL FROM D-GALACTONOLACTONE AND SYNTHESES OF 1,4-DIDEOXY-1,4-IMINO-D-ALLITOL, 1,4-DIDEOXY-1,4-IMINO-D-RIBITOL, AND (2S,3R,4S)-3,4-DIHYDROXYPROLINE FROM D-GULONOLACTONE
著者:: Fleet, G, 等
出版事項: (1988)

Crystal structure of 1,4-dideoxy-1,4-imino-D-mannitol hydrochloride, C6H14ClNO4
著者:: Henkel S., 等
出版事項: (1997-12-01)

Crystal structure of 1,4-dideoxy-1,4-imino-D-mannitol hydrochloride, C6H14ClNO4
著者:: Henkel S., 等
出版事項: (1997-12-01)

1,4-Dideoxy-1,4-imino‑d‑arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α‑Mannosidase Inhibitors
著者:: Marianne B. Haarr, 等
出版事項: (2020-07-01)

An alpha-glucoside of 1,4-dideoxy-1,4-imino-D-lyxitol with an eleven carbon side chain
著者:: Kato, A, 等
出版事項: (2010)

3,6-dideoxy-3,6-imino-1,2-o-isopropylidene-α-d-glucofuranose as a divergent intermediate for the synthesis of hydroxylated pyrrolidines; synthesis of 1,4 dideoxy-1,4-imino-l-gulitol,...
著者:: Fleet, G, 等
出版事項: (1987)

3,6-DIDEOXY-3,6-IMINO-1,2-O-ISOPROPYLIDENE-ALPHA-D-GLUCOFURANOSE AS A DIVERGENT INTERMEDIATE FOR THE SYNTHESIS OF HYDROXYLATED PYRROLIDINES - SYNTHESIS OF 1,4-DIDEOXY-1,4-IMINO-L-GULITOL, 1,4-DIDEOXY-1,4-IMINO-D-LYXITOL, 2S,3S,4R-3,4-DIHYDROXYPROLINE AND (1S,2R,8S,8AR)-1,2,8-TRIHYDROXYOCTAHYDROINDOLIZINE [8-EPI-SWAINSONINE] - X-RAY CRYSTAL-STRUCTURE OF (1S,2R,8S,8AR)-1,2,8-TRIHYDROXY-5-OXO-OCTAHYDROINDOLIZINE
著者:: Austin, G, 等
出版事項: (1987)

Convenient Synthesis of 1,4-Dideoxy-1,4-imino-D-ribitol from D-Ribose
著者:: Makoto Oba, 等
出版事項: (2013-01-01)

SYNTHESIS FROM D-LYXONOLACTONE OF 1,4-DIDEOXY-1,4-IMINO-L-ARABINITOL, A GLUCOSIDASE INHIBITOR WITH INVITRO ANTIVIRAL ACTIVITY
著者:: Behling, J, 等
出版事項: (1993)

Preliminary studies on the transformation of nitrosugars into branched chain iminosugars: synthesis of 1,4-dideoxy-4-C-hydroxymethyl-1,4-imino-pentanols.
著者:: Otero, J, 等
出版事項: (2007)

Crystal structure of 1,4-dideoxy-1,4-imino-D-gulitol hydrochloride, C6H14CINO4
著者:: Henkel S., 等
出版事項: (1997-12-01)

Crystal structure of 1,4-dideoxy-1,4-imino-D-gulitol hydrochloride, C6H14CINO4
著者:: Henkel S., 等
出版事項: (1997-12-01)

STRUCTURE ACTIVITY RELATIONSHIP OF SWAINSONINE - INHIBITION OF HUMAN ALPHA-MANNOSIDASES BY SWAINSONINE ANALOGS
著者:: Dibello, I, 等
出版事項: (1989)

Looking glass inhibitors: both enantiomeric N-benzyl derivatives of 1,4-dideoxy-1,4-imino-D-lyxitol [a potent competitive inhibitor of alpha-D-galactosidase] and of 1,4-dideoxy-1,4-imino-L-lyxitol [a weak competitive inhibitor of alpha-D-galactosidase] inhibit naringinase, an alpha-L-rhamnosidase competitively
著者:: Mercer, T, 等
出版事項: (2009)

SYNTHESIS OF 1,5-DIDEOXY-3-O-(ALPHA-D-MANNOPYRANOSYL)-1,5-IMINO-D-MANNITOL AND 1,5-DIDEOXY-3-O-(ALPHA-D-GLUCOPYRANOSYL)-1,5-IMINO-D-MANNITOL - POWERFUL INHIBITORS OF ENDOMANNOSIDASE
著者:: Ardron, H, 等
出版事項: (1993)

SYNTHESES OF 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL FROM D-MANNOSE AND FROM D-GLUCOSE
著者:: Fleet, G, 等
出版事項: (1984)

Enantiomeric 2-acetamido-1,4-dideoxy-1,4-iminoribitols as potential pyrrolidine hexosaminidase inhibitors
著者:: Rountree, J, 等
出版事項: (2011)

3-O-Benzhydryl-2,5-dideoxy-2,5-imino-2-C-methyl-l-lyxono-1,4-lactone
著者:: David J. Watkin, 等
出版事項: (2008-10-01)

Hydroxymethyl-Branched Piperidines from Hydroxymethyl-Branched Lactones: Synthesis and Biological Evaluation of 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-D-mannitol, 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-L-gulitol and 1,5-Dideoxy-2-C-hydroxymethyl-1,5-imino-D-talitol
著者:: Soengas, R, 等
出版事項: (2012)

SYNTHESIS OF HOMOCHIRAL BETA-HYDROXY-ALPHA-AMINO-ACIDS [(2S,3R,4R)-3,4-DIHYDROXYPROLINE AND (2S,3R,4R)-3,4-DIHYDROXYPIPECOLIC ACID] AND OF 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL [DAB1] AND FAGOMINE [1,5-IMINO-1,2,5-TRIDEOXY-D-ARABINO-HEXITOL]
著者:: Fleet, G, 等
出版事項: (1990)

Synthesis of homochiral β-hydroxy-α-aminoacids [(2S,3R,4R)-3,4-dihydroxyproline and (2S,3R,4R)-3,4-dihydroxypipecolic aicd] and of 1,4-dideoxy-1,4-imino-D-arabinitol [DAB1] and fagomine [1,5-imino-1,2,5-trideoxy-D-arabino-hexitol]
著者:: Fleet, G, 等
出版事項: (1990)

Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases
著者:: Maroš Bella, 等
出版事項: (2018-08-01)

N-Benzyl-1, 3-dideoxy-1, 3-imino-L-xylitol
著者:: Jenkinson, S, 等
出版事項: (2011)

Synthesis, α-mannosidase inhibition studies and molecular modeling of 1,4-imino-ᴅ-lyxitols and their C-5-altered N-arylalkyl derivatives
著者:: Martin Kalník, 等
出版事項: (2023-03-01)

2-Acetamido-N-benzyl-1,4-imino-1,2,4-trideoxy-L-ribitol
著者:: Harding, C, 等
出版事項: (2005)

Structural and biochemical characterization of the Cutibacterium acnes exo-β-1,4-mannosidase that targets the N-glycan core of host glycoproteins.
著者:: Tom Reichenbach, 等
出版事項: (2018-01-01)

SYNTHESIS OF DEOXYMANNOJIRIMYCIN FAGOMINE DEOXYNOJIRIMYCIN 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-MANNITOL 2-ACETAMIDO-1,5-IMINO-1,2,5-TRIDEOXY-D-GLUCITOL 2S, 3R, 4R, 5R-TRIHYDROXYPIPECOLIC ACID AND 2S, 3R, 4R, 5S-TRIHYDROXYPIPECOLIC ACID FROM METHYL 3-O-BENZYL-2,6-DIDEOXY-2,6-IMINO-ALPHA-D-MANNOFURANOSIDE
著者:: Fleet, G, 等
出版事項: (1987)

L-(+)-swainsonine and other pyrrolidine inhibitors of naringinase: Through an enzymic looking glass from D-mannosidase to L-rhamnosidase?
著者:: Davis, B, 等
出版事項: (1996)

2-Acetamido-N-benzyl-1,4-imino-1,2,4-trideoxy-L-arabinitol 0.33-hydrate
著者:: Harding, C, 等
出版事項: (2005)