Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish.

Ligands of the transforming growth factor beta (TGFbeta) superfamily, like Nodal and bone morphogenetic protein (BMP), are pivotal to establish left-right (LR) asymmetry in vertebrates. However, the receptors mediating this process are unknown. Here we identified two new type II receptors for BMPs i...

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Bibliographic Details
Main Authors: Monteiro, R, van Dinther, M, Bakkers, J, Wilkinson, R, Patient, R, ten Dijke, P, Mummery, C
Format: Journal article
Language:English
Published: 2008