Genetic mechanisms of critical illness in COVID-19

Genetic mechanisms of critical illness in COVID-19

<p>Host-mediated lung inflammation is present<sup>1</sup>, and drives mortality<sup>2</sup>, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic de...

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Main Authors: Pairo-Castineira, E, Clohisey, S, Klaric, L, Bretherick, AD, Rawlik, K, Pasko, D, Walker, S, Parkinson, N, Fourman, MH, Russell, CD, Furniss, J, Richmond, A, Gountouna, E, Wrobel, N, Harrison, D, Wang, B, Wu, Y, Meynert, A, Griffiths, F, Oosthuyzen, W, Kousathanas, A, Moutsianas, L, Yang, Z, Zhai, R, Zheng, C, Grimes, G, Beale, R, Millar, J, Shih, B, Keating, S, Zechner, M, Haley, C, Porteous, DJ, Hayward, C, Yang, J, Knight, J, Summers, C, Shankar-Hari, M, Klenerman, P, Turtle, L, Ho, A, Moore, SC, Hinds, C, Horby, P, Nichol, A, Maslove, D, Ling, L, McAuley, D, Montgomery, H, Walsh, T
Format: Journal article
Language:English
Published: Nature Research 2020

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