Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track

Molecular motors employ chemical energy to generate unidirectional mechanical output against a track while navigating a chaotic cellular environment, potential disorder on the track, and against Brownian motion. Nevertheless, decades of nanometer-precise optical studies suggest that myosin-5a, one o...

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Bibliographic Details
Main Authors: Fineberg, A, Takagi, Y, Thirumurugan, K, Andrecka, J, Billington, N, Young, G, Cole, D, Burgess, SA, Curd, AP, Hammer, JA, Sellers, JR, Kukura, P, Knight, PJ
Format: Journal article
Language:English
Published: National Academy of Sciences 2024