Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track
Molecular motors employ chemical energy to generate unidirectional mechanical output against a track while navigating a chaotic cellular environment, potential disorder on the track, and against Brownian motion. Nevertheless, decades of nanometer-precise optical studies suggest that myosin-5a, one o...
Main Authors: | Fineberg, A, Takagi, Y, Thirumurugan, K, Andrecka, J, Billington, N, Young, G, Cole, D, Burgess, SA, Curd, AP, Hammer, JA, Sellers, JR, Kukura, P, Knight, PJ |
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Format: | Journal article |
Language: | English |
Published: |
National Academy of Sciences
2024
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