LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly
Dysregulated endogenous retroelements (EREs) are increasingly implicated in the initiation, progression, and immune surveillance of human cancer. However, incomplete knowledge of ERE activity limits mechanistic studies. By using pan-cancer de novo transcript assembly, we uncover the extent and compl...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2019
|