Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme

Since their initial characterization over 30 years ago, it has been believed that the archaeal B-family DNA polymerases are single-subunit enzymes. This contrasts with the multi-subunit B-family replicative polymerases of eukaryotes. Here we reveal that the highly studied PolB1 from Sulfolobus solfa...

Full description

Bibliographic Details
Main Authors: Yan, J, Beattie, T, Rojas, A, Schermerhorn, K, Gristwood, T, Trinidad, J, Albers, S, Roversi, P, Gardner, A, Abrescia, N, Bell, S
Format: Journal article
Language:English
Published: Springer Nature 2017