Olaparib increases the therapeutic index of hemithoracic irradiation compared with hemithoracic irradiation alone in a mouse lung cancer model

<strong>Background</strong> The radiosensitising effect of the poly(ADP-ribose) polymerase inhibitor olaparib on tumours has been reported. However, its effect on normal tissues in combination with radiation has not been well studied. Herein, we investigated the therapeutic index of olap...

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Bibliographic Details
Main Authors: Jiang, Y, Martin, J, Alkadhimi, M, Shigemori, K, Kinchesh, P, Gilchrist, S, Kersemans, V, Smart, S, Thompson, JM, Hill, MA, O'Connor, MJ, Davies, BR, Ryan, AJ
Format: Journal article
Language:English
Published: Springer Nature 2021