DNA mismatch repair preferentially protects genes from mutation

Mutation is the source of genetic variation and fuels biological evolution. Many mutations first arise as DNA replication errors. These errors subsequently evade correction by cellular DNA repair, for example, by the well-known DNA mismatch repair (MMR) mechanism. Here, we determine the genome-wide...

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Bibliografiske detaljer
Main Authors: Belfield, E, Ding, Z, Jamieson, F, Visscher, A, Zheng, S, Mithani, A, Harberd, N
Format: Journal article
Sprog:English
Udgivet: Cold Spring Harbor Laboratory Press 2017