DNA mismatch repair preferentially protects genes from mutation

Mutation is the source of genetic variation and fuels biological evolution. Many mutations first arise as DNA replication errors. These errors subsequently evade correction by cellular DNA repair, for example, by the well-known DNA mismatch repair (MMR) mechanism. Here, we determine the genome-wide...

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Hlavní autoři: Belfield, E, Ding, Z, Jamieson, F, Visscher, A, Zheng, S, Mithani, A, Harberd, N
Médium: Journal article
Jazyk:English
Vydáno: Cold Spring Harbor Laboratory Press 2017