DNA mismatch repair preferentially protects genes from mutation

Mutation is the source of genetic variation and fuels biological evolution. Many mutations first arise as DNA replication errors. These errors subsequently evade correction by cellular DNA repair, for example, by the well-known DNA mismatch repair (MMR) mechanism. Here, we determine the genome-wide...

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Autori principali: Belfield, E, Ding, Z, Jamieson, F, Visscher, A, Zheng, S, Mithani, A, Harberd, N
Natura: Journal article
Lingua:English
Pubblicazione: Cold Spring Harbor Laboratory Press 2017