DNA mismatch repair preferentially protects genes from mutation

Mutation is the source of genetic variation and fuels biological evolution. Many mutations first arise as DNA replication errors. These errors subsequently evade correction by cellular DNA repair, for example, by the well-known DNA mismatch repair (MMR) mechanism. Here, we determine the genome-wide...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Belfield, E, Ding, Z, Jamieson, F, Visscher, A, Zheng, S, Mithani, A, Harberd, N
Format: Journal article
Sprache:English
Veröffentlicht: Cold Spring Harbor Laboratory Press 2017