Meisetz and the birth of the KRAB motif.
The largest family of transcription factors in mammals is of Cys(2)His(2) zinc finger-proteins, each with an NH(2)-terminal KRAB motif. Extensive expansions of this family have occurred in separate mammalian lineages, with approximately 400 such genes known in the human genome. Despite their widespr...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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