FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma.

FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma.

FOXP3 is a forkhead transcription factor family member, implicated in T-cell regulation, activation and differentiation. FOXP3 has been shown to be a master control gene for the development and function of CD4+/CD25+ regulatory T-cells (T(reg)). In this study, FOXP3 protein expression has been analy...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Roncador, G, Garcia, J, Maestre, L, Lucas, E, Menarguez, J, Ohshima, K, Nakamura, S, Banham, A, Piris, M
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2005

Antzeko izenburuak

FOXP3 expression in B and T cell lymphomas.
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Strong expression of FOXP1 identifies a distinct subset of diffuse large B-cell lymphoma (DLBCL) patients with poor outcome.
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Genetic rearrangement of FOXP1 is predominantly detected in a subset of diffuse large B-cell lymphomas with extranodal presentation.
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Is FOXP3 expressed in cutaneous T-cell lymphomas?
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The FOXP3 transcription factor as a regulatory T-cell marker
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High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma.
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Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells.
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Expression of FOXP2 is up-regulated in lymphoid malignancies
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Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sezary syndrome from other cutaneous T-cell lymphomas.
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FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures
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The FOXP1 transcription factor is expressed in the majority of follicular lymphomas but is rarely expressed in classical and lymphocyte predominant Hodgkin's lymphoma.
nork: Brown, P, et al.
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Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level.
nork: Roncador, G, et al.
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Aggressive large B-cell lymphoma with plasma cell differentiation: immunohistochemical characterization of plasmablastic lymphoma and diffuse large B-cell lymphoma with partial plasmablastic phenotype
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FOXP1 abnormalities in lymphoma: Translocation breakpoint mapping reveals insights into deregulated transcriptional control
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Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.
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Therapeutic targeting of FOXP3-positive regulatory T cells using a FOXP3 peptide vaccine WO2008081581.
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Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells: Research paper
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MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas.
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Ataxia telangiectasia gene mutations in leukaemia and lymphoma.
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Deregulated over expression of FOXP1 protein in diffuse large B-cell lymphoma does not occur as a result of gene rearrangement.
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Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma.
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Adult T-cell leukaemia/lymphoma in an adolescent patient: Expect the unexpected
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FOXP3+ regulatory T cells as biomarkers in human malignancies.
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FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment.
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Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia.
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Strong expression of FOXP1 predicts for poor prognosis within the non-germinal centre subgroup of diffuse large B cell lymphoma
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t(3;14)(p14;q32) results in aberrant expression of FOXP1 in a case of diffuse large B-cell lymphoma.
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Monoclonal antibodies raised to the human FOXP3 protein can be used effectively for detecting Foxp3(+) T cells in other mammalian species.
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The epidemiology of leukaemias and lymphomas: a review.
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Therapeutic Modulation of Autophagy in Leukaemia and Lymphoma
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CRISPR/Cas9-mediated Foxp1 silencing restores immune surveillance in an immunocompetent A20 lymphoma model
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Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells.
nork: Banham, A
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Bcl-2 but not FOXP1, is an adverse risk factor in immunochemotherapy-treated non-germinal center diffuse large B-cell lymphomas.
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