Recent advances in modelling of cerebellar ataxia using induced pluripotent stem cells

The cerebellar ataxias are a group of incurable brain disorders that are caused primarily by the progressive dysfunction and degeneration of cerebellar Purkinje cells. The lack of reliable disease models for the heterogeneous ataxias has hindered the understanding of the underlying pathogenic mechan...

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Bibliographic Details
Main Authors: Wong, M, Watson, L, Becker, E
Format: Journal article
Published: SciAccess Publishers 2017