The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells

The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells

Regulatory T cells (Tregs) have a central role in maintaining immune homoeostasis through various mechanisms. Although the Forkhead transcription factor Foxp3 defines the Treg cell lineage and functions, the molecular mechanisms of Foxp3 induction and maintenance remain elusive. Here we show that Fo...

Полное описание

Библиографические подробности
Главные авторы:	Sekiya, T, Kashiwagi, I, Inoue, N, Morita, R, Hori, S, Waldmann, H, Rudensky, A, Ichinose, H, Metzger, D, Chambon, P, Yoshimura, A
Формат:	Journal article
Язык:	English
Опубликовано:	Springer Nature 2011

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