IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals.

Dendritic cells (DCs) are the professional APCs of the immune system, enabling T cells to perceive and respond appropriately to potentially dangerous microbes, while also being able to maintain T cell tolerance toward self. In part, such tolerance can be determined by IL-10 released from certain typ...

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Bibliographic Details
Main Authors: Nolan, K, Strong, V, Soler, D, Fairchild, P, Cobbold, S, Croxton, R, Gonzalo, J, Rubio, A, Wells, M, Waldmann, H
Format: Journal article
Language:English
Published: 2004