Actin nucleation by a transcription co-factor that links cytoskeletal events with the p53 response.

Despite its obvious importance in tumorigenesis, little information is available on the mechanisms that integrate cell motility and invasion with nuclear events.  Tumor suppressor p53 is a DNA damage responsive transcription factor which initiates a checkpoint response culminating in cell cycle arre...

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Bibliographic Details
Main Authors: Coutts, A, Weston, L, La Thangue, N
Format: Journal article
Language:English
Published: 2010