Actin nucleation by a transcription co-factor that links cytoskeletal events with the p53 response.

Actin nucleation by a transcription co-factor that links cytoskeletal events with the p53 response.

Despite its obvious importance in tumorigenesis, little information is available on the mechanisms that integrate cell motility and invasion with nuclear events. Tumor suppressor p53 is a DNA damage responsive transcription factor which initiates a checkpoint response culminating in cell cycle arre...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Coutts, A, Weston, L, La Thangue, N
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2010

Eitemau Tebyg

Actin nucleators in the nucleus: an emerging theme.
gan: Weston, L, et al.
Cyhoeddwyd: (2012)

p53-cofactor JMY is a multifunctional actin nucleation factor.
gan: Zuchero, J, et al.
Cyhoeddwyd: (2009)

A transcription co-factor integrates cell adhesion and motility with the p53 response.
gan: Coutts, A, et al.
Cyhoeddwyd: (2009)

Regulation of actin nucleation and autophagosome formation.
gan: Coutts, A, et al.
Cyhoeddwyd: (2016)

Actin nucleation by WH2 domains at the autophagosome.
gan: Coutts, A, et al.
Cyhoeddwyd: (2015)

Mdm2 targets the p53 transcription cofactor JMY for degradation.
gan: Coutts, A, et al.
Cyhoeddwyd: (2007)

JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues.
gan: Adighibe, O, et al.
Cyhoeddwyd: (2014)

Arabidopsis Actin-Depolymerizing Factor-4 links pathogen perception, defense activation and transcription to cytoskeletal dynamics.
gan: Katie Porter, et al.
Cyhoeddwyd: (2012-01-01)

p53 ubiquitination by Mdm2: a never ending tail?
gan: Coutts, A, et al.
Cyhoeddwyd: (2009)

Actin dynamics and the elasticity of cytoskeletal networks
Cyhoeddwyd: (2009-09-01)

Actin binding domains direct actin-binding proteins to different cytoskeletal locations
gan: Washington Raymond W, et al.
Cyhoeddwyd: (2008-02-01)

Cytoskeletal actin patterns shape mast cell activation
gan: Colin-York, H, et al.
Cyhoeddwyd: (2019)

Turning the Actin Nucleating Compound Miuraenamide into Nucleation Inhibitors
gan: Shuaijun Wang, et al.
Cyhoeddwyd: (2021-08-01)

Lysine methylation and the regulation of p53.
gan: Carr, S, et al.
Cyhoeddwyd: (2012)

Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation
gan: Fritzsche, M, et al.
Cyhoeddwyd: (2017)

Arginine methylation regulates the p53 response.
gan: Jansson, M, et al.
Cyhoeddwyd: (2008)

Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.
gan: Maniam, S, et al.
Cyhoeddwyd: (2015)

Direct Visualization and Quantification of the Actin Nucleation and Elongation Events in vitro by TIRF Microscopy
gan: Yuxiang Jiang, et al.
Cyhoeddwyd: (2017-03-01)

Self-organizing actin patterns shape cytoskeletal cortex organization
gan: Fritzsche, M
Cyhoeddwyd: (2017)

Endometriosis and Cytoskeletal Remodeling: The Functional Role of Actin-Binding Proteins
gan: Wioletta Arendt, et al.
Cyhoeddwyd: (2025-02-01)

Alteration of actin cytoskeletal organisation in fetal akinesia deformation sequence
gan: Ramona Jühlen, et al.
Cyhoeddwyd: (2024-01-01)

Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization[S]
gan: Akua N. Roach, et al.
Cyhoeddwyd: (2012-12-01)

p53 methylation--the Arg-ument is clear.
gan: Durant, S, et al.
Cyhoeddwyd: (2009)

Quantitative mass imaging of actin nucleation
gan: Hundt, N, et al.
Cyhoeddwyd: (2019)

ATM and Chk2 kinase target the p53 cofactor Strap.
gan: Adams, C, et al.
Cyhoeddwyd: (2008)

NET4 and RabG3 link actin to the tonoplast and facilitate cytoskeletal remodelling during stomatal immunity
gan: Timothy J. Hawkins, et al.
Cyhoeddwyd: (2023-09-01)

The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.
gan: Adams, C, et al.
Cyhoeddwyd: (2012)

Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis
gan: Coutts, A, et al.
Cyhoeddwyd: (2018)

MICAL-mediated oxidation of actin and its effects on cytoskeletal and cellular dynamics
gan: Sudeepa Rajan, et al.
Cyhoeddwyd: (2023-02-01)

Extraction of accurate cytoskeletal actin velocity distributions from noisy measurements
gan: Cayla M. Miller, et al.
Cyhoeddwyd: (2022-08-01)

A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin.
gan: Yao Liu, et al.
Cyhoeddwyd: (2017-01-01)

Actin nucleation at the centrosome controls lymphocyte polarity
gan: Dorian Obino, et al.
Cyhoeddwyd: (2016-03-01)

Huntington’s Disease—An Outlook on the Interplay of the HTT Protein, Microtubules and Actin Cytoskeletal Components
gan: Aleksandra S. Taran, et al.
Cyhoeddwyd: (2020-06-01)

Structural Inheritance of the Actin Cytoskeletal Organization Determines the Body Axis in Regenerating Hydra
gan: Anton Livshits, et al.
Cyhoeddwyd: (2017-02-01)

Cytoskeletal dysregulation and neurodegenerative disease: Formation, monitoring, and inhibition of cofilin-actin rods
gan: Anna I. Wurz, et al.
Cyhoeddwyd: (2022-09-01)

E2F-7 couples DNA damage-dependent transcription with the DNA repair process.
gan: Zalmas, L, et al.
Cyhoeddwyd: (2013)

Links of Cytoskeletal Integrity with Disease and Aging
gan: Yu Jin Kim, et al.
Cyhoeddwyd: (2022-09-01)

Cytokinesis requires localized β-actin filament production by an actin isoform specific nucleator
gan: A. Chen, et al.
Cyhoeddwyd: (2017-11-01)

Cofactor strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase
gan: Maniam, Sandra, et al.
Cyhoeddwyd: (2015)

p53 and MDM2 protein expression in actinic cheilitis
gan: Maria da Conceição Andrade de Freitas, et al.
Cyhoeddwyd: (2008-12-01)