Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells.

Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells.

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that can be used for vaccination purposes, to induce a specific T-cell response in vivo against melanoma-associated antigens. We have shown that the sequential use of early-acting hematopoietic growth factors, stem cell factor, I...

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Bibliografiska uppgifter
Huvudupphovsmän: Mackensen, A, Herbst, B, Chen, J, Köhler, G, Noppen, C, Herr, W, Spagnoli, G, Cerundolo, V, Lindemann, A
Materialtyp: Journal article
Språk:English
Publicerad: 2000

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