Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence.

Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence.

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The family of CD1 molecules is structurally similar to MHC class I molecules, but the 2 protein families mediate fundamentally different immune functions. MHC class I molecules present peptides to T cells, whereas CD1 molecules present lipids to natural killer T cells and other CD1-restricted T cell...

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Hlavní autoři: Cerny, D, Thi Le, D, The, T, Zuest, R, Kg, S, Velumani, S, Khor, C, Mori, L, Simmons, C, Poidinger, M, Zolezzi, F, Ginhoux, F, Haniffa, M, Wills, B, Fink, K
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2016

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