Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence.
The family of CD1 molecules is structurally similar to MHC class I molecules, but the 2 protein families mediate fundamentally different immune functions. MHC class I molecules present peptides to T cells, whereas CD1 molecules present lipids to natural killer T cells and other CD1-restricted T cell...
| Auteurs principaux: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
Elsevier
2016
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